SCHEMBL19970595

SCHEMBL19970595

CCCCCCCCCC[Si](OC)OC

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
THRB P10828 1/20 0.44
DNM1 Q05193 7/20 0.35
ALDH1A1 P00352 3/20 0.35
LMNA P02545 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HSD17B10 Q99714 1/20 0.35
SLC22A1 O15245 1/20 0.35
EPHX1 P07099 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19970584 1.00 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL5150115 1.00 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL28157254 1.00 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL26691441 1.00 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL27599928 1.00 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL23365107 1.00 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL23365089 0.97 TSHR (0.39) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL340148 0.88
SCHEMBL28290073 0.82 TSHR (0.32) TSHRTHRB
SCHEMBL23365104 0.78 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107531492-B Aminosilane-modified colloidal silica dispersion and method for producing same 日产化学工业株式会社 2021-03-12 CN claimed
US-10899893-B2 Aminosilane-modified colloidal silica dispersion and method of manufacturing same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2021-01-26 US claimed
US-20180355117-A1 AMINOSILANE-MODIFIED COLLOIDAL SILICA DISPERSION AND METHOD OF MANUFACTURING SAME NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-12-13 US claimed
EP-3296262-A1 AMINOSILANE-MODIFIED COLLOIDAL SILICA DISPERSION AND METHOD OF MANUFACTURING SAME Nissan Chemical Industries, Ltd. (JP) 2018-03-21 EP claimed
CN-107531492-B Aminosilane-modified colloidal silica dispersion and method for producing same 日产化学工业株式会社 2021-03-12 CN disclosed
US-10899893-B2 Aminosilane-modified colloidal silica dispersion and method of manufacturing same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2021-01-26 US disclosed
US-20180355117-A1 AMINOSILANE-MODIFIED COLLOIDAL SILICA DISPERSION AND METHOD OF MANUFACTURING SAME NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-12-13 US disclosed
EP-3296262-A1 AMINOSILANE-MODIFIED COLLOIDAL SILICA DISPERSION AND METHOD OF MANUFACTURING SAME Nissan Chemical Industries, Ltd. (JP) 2018-03-21 EP disclosed