Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21292608 | 0.92 | KMT2A (0.44) | KMT2AKDM4ELMNAALDH1A1HSD17B10 | |
| SCHEMBL21292610 | 0.92 | KMT2A (0.44) | KMT2AKDM4ELMNAALDH1A1HSD17B10 | |
| SCHEMBL21292647 | 0.88 | KMT2A (0.43) | KMT2AKDM4ELMNAALDH1A1HSD17B10 | |
| SCHEMBL21292644 | 0.88 | KMT2A (0.43) | KMT2AKDM4ELMNAALDH1A1HSD17B10 | |
| SCHEMBL19971539 | 0.86 | KMT2A (0.40) | KMT2AKDM4ELMNAALDH1A1HSD17B10 | |
| SCHEMBL19971538 | 0.86 | KMT2A (0.40) | KMT2AKDM4ELMNAALDH1A1HSD17B10 | |
| SCHEMBL19986883 | 0.85 | KMT2A (0.47) | KMT2AKDM4ELMNAALDH1A1HSD17B10 | |
| SCHEMBL19971432 | 0.85 | KMT2A (0.47) | KMT2AKDM4ELMNAALDH1A1HSD17B10 | |
| SCHEMBL21292630 | 0.85 | KMT2A (0.47) | KMT2AKDM4ELMNAALDH1A1HSD17B10 | |
| SCHEMBL29980728 | 0.85 | KMT2A (0.44) | KMT2AKDM4ELMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512849-B1 | 7-SUBSTITUTED 1-ARYL-NAPHTHYRIDIN-3-CARBOXAMIDES AND THEIR USE | BAYER AG (DE) | 2021-06-23 | — | — | EP | disclosed |
| EP-3296298-A1 | 7-SUBSTITUTED 1-ARYL-NAPHTHYRIDIN-3-CARBOXAMIDES AND THEIR USE | Bayer Pharma Aktiengesellschaft (DE) | 2018-03-21 | — | — | EP | disclosed |