SCHEMBL1997151

SCHEMBL1997151

O=C(OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.53
USP2 O75604 1/20 0.53
MAPT P10636 1/20 0.53
MAPK1 P28482 1/20 0.53
HIF1A Q16665 1/20 0.53
ALDH1A1 P00352 3/20 0.44
TDP1 Q9NUW8 3/20 0.42
SLC6A3 Q01959 2/20 0.42
HTR1A P08908 1/20 0.42
CYP2D6 P10635 1/20 0.42
SCN1A P35498 1/20 0.42
SCN5A Q14524 1/20 0.42
SCN2A Q99250 1/20 0.42
SCN3A Q9NY46 1/20 0.42
KMT2A Q03164 3/20 0.41
SLC6A2 P23975 1/20 0.41
LMNA P02545 3/20 0.41
ADRB2 P07550 2/20 0.39
ADRB1 P08588 2/20 0.39
ADRB3 P13945 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13252215 1.00 TSHR (0.53) TSHRUSP2MAPTMAPK1HIF1A
SCHEMBL1998953 0.94 MAPK1 (0.56) TSHRUSP2MAPTMAPK1HIF1A
SCHEMBL12269819 0.89 MAPK1 (0.65) TSHRMAPK1HIF1AALDH1A1TDP1
SCHEMBL12269823 0.89 MAPK1 (0.65) TSHRMAPK1HIF1AALDH1A1TDP1
SCHEMBL12269832 0.89 MAPK1 (0.65) TSHRMAPK1HIF1AALDH1A1TDP1
SCHEMBL14522616 0.87 TSHR (0.51) TSHRUSP2MAPTMAPK1HIF1A
SCHEMBL1993316 0.85 MAPK1 (0.59) TSHRMAPK1HIF1AALDH1A1TDP1
SCHEMBL1998327 0.85 MAPK1 (0.59) TSHRMAPK1HIF1AALDH1A1TDP1
SCHEMBL12269882 0.84 MAPK1 (0.57) TSHRMAPK1HIF1AALDH1A1TDP1
SCHEMBL12269996 0.84 MAPK1 (0.57) TSHRMAPK1HIF1AALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US disclosed
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed
US-20070077373-A1 Polymer film and polarizing plate and liquid crystal display device using the same FUJI PHOTO FILM CO., LTD. (JP) 2007-04-05 US disclosed