SCHEMBL19971980

SCHEMBL19971980

CCCCCCCCCCC(CCCCCCCC)CCCCCCCc1cc(-c2ccc(-c3cc(CCCCCCCC(CCCCCCCC)CCCCCCCCCC)c(Br)s3)c3nsnc23)sc1Br

nearest known ligand 0.30

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.30
▸ TP53 P04637 1/20 0.30
▸ CYP3A4 P08684 1/20 0.30
▸ ALOX5 P09917 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ TYR P14679 1/20 0.30
▸ ALOX15 P16050 1/20 0.30
▸ TSHR P16473 1/20 0.30
▸ HTT P42858 1/20 0.30
▸ KMT2A Q03164 1/20 0.30
▸ TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL860366 0.93 TYR (0.34) MEN1TP53CYP3A4ALOX5MAPT
SCHEMBL16111624 0.93 TYR (0.34) MEN1TP53CYP3A4ALOX5MAPT
SCHEMBL1395790 0.93 TYR (0.34) MEN1TP53CYP3A4ALOX5MAPT
SCHEMBL19240265 0.89 — —
SCHEMBL19410237 0.89 — —
SCHEMBL14217361 0.89 — —
SCHEMBL28699900 0.89 SMN1; SMN2 (0.35) MEN1TP53MAPTHTTKMT2A
SCHEMBL12587620 0.89 MEN1 (0.32) MEN1TP53CYP3A4ALOX5MAPT
SCHEMBL19476972 0.89 — —
SCHEMBL17300593 0.87 TYR (0.31) MEN1TP53CYP3A4ALOX5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109715696-B Fused thiophene-arylthiadiazole polymers, methods of making the same, and uses thereof 康宁股份有限公司 2022-03-04 — — CN disclosed
US-10759898-B2 Fused thiophene-arylthiadiazole polymers, methods of making such polymers, and uses thereof CORNING INCORPORATED (US) 2020-09-01 — — US disclosed
US-20180079858-A1 FUSED THIOPHENE-ARYLTHIADIAZOLE POLYMERS, METHODS OF MAKING SUCH POLYMERS, AND USES THEREOF CORNING INCORPORATED 2018-03-22 — — US disclosed
WO-2018053226-A1 FUSED THIOPHENE-ARYLTHIADIAZOLE POLYMERS, METHODS OF MAKING SUCH POLYMERS, AND USES THEREOF CORNING INCORPORATED (US) 2018-03-22 — — WO disclosed
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