SCHEMBL199726

SCHEMBL199726

Oc1ccc(Cl)nc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29776734 1.00
SCHEMBL25415014 0.97
Methane SCHEMBL9666532 0.97
Acetone SCHEMBL2165790 0.89 NAPRT (0.50)
SCHEMBL27586878 0.80 PIK3CD (0.57)
SCHEMBL28438899 0.75 MEN1 (0.56)
SCHEMBL1662273 0.71 PIK3CD (0.73)
SCHEMBL174894 0.71
SCHEMBL30958843 0.71 CCR1 (0.46)
SCHEMBL17800 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1724 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115652649-A Preparation method of water pressure resistant down jacket fabric 福建佳来户外服装有限公司 2023-01-31 CN claimed
CN-110128615-B Waterborne polyurethane and preparation method and application thereof 江苏奥斯佳材料科技股份有限公司 2022-04-15 CN claimed
US-20190016745-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2019-01-17 US claimed
EP-3400231-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS Technion Research & Development Foundation Limited (IL) 2018-11-14 EP claimed
EP-3344641-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS Eloxx Pharmaceuticals Ltd. (IL) 2018-07-11 EP claimed
WO-2017118967-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2017-07-13 WO claimed
US-9643933-B2 Compounds useful as antibiotic tolerance inhibitors THE GENERAL HOSPITAL CORPORATION (US) 2017-05-09 US claimed
WO-2017037719-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS ELOXX PHARMACEUTICALS LTD. (IL) 2017-03-09 WO claimed
US-20160052890-A1 COMPOUNDS USEFUL AS ANTIBIOTIC TOLERANCE INHIBITORS THE GENERAL HOSPITAL CORPORATION (US) 2016-02-25 US claimed
CN-103396465-B A kind of Avrmectin nicotine two is tired compound and Synthesis and applications thereof INSTITUTE OF PLANT PROTECTION CHINESE ACADEMY OF AGRICULTURAL SCIENCES (CN) 2016-01-20 CN claimed
WO-2014176258-A1 COMPOUNDS USEFUL AS ANTIBIOTIC TOLERANCE INHIBITORS THE GENERAL HOSPITAL CORPORATION (US) 2014-10-30 WO claimed
US-7405221-B2 Substituted pyrimidines MERCK & CO., INC. (US) 2008-07-29 US claimed
US-20050245554-A1 Substituted pyrimidines MERCK SHARP & DOHME CORP. 2005-11-03 US claimed
EP-1546115-A2 SUBSTITUTED PYRIMIDINES Merck & Co., Inc. (US) 2005-06-29 EP claimed
WO-2004029204-A2 SUBSTITUTED PYRIMIDINES MERCK & CO., INC. (US) 2004-04-08 WO claimed
EP-4743456-A1 COMPOUNDS, PREPARATION METHODS AND USES THEREOF InventisBio Co., Ltd. (CN) 2026-05-20 EP disclosed
EP-4294781-B1 CATALYTIC METHOD FOR THE PREPARATION OF PERFLUOROALKOXY-SUBSTITUTED ARENES AND HETEROARENES UNIV BERLIN FREIE (DE) 2026-05-20 EP disclosed
EP-0002678-B1 AZOLYLALKYL-PYRIDINYL ETHERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1981-12-30 EP disclosed
EP-0032561-A1 Triazolylphenacyl-pyridyl-ether derivatives, process for their preparation and their application as fungicides BAYER AG (DE) 1981-07-29 EP disclosed
EP-0002678-A2 Azolylalkyl-pyridinyl ethers, process for their preparation and their use as fungicides BAYER AG (DE) 1979-07-11 EP disclosed