SCHEMBL1997263

SCHEMBL1997263

CCC(CC)(CCOCC1CO1)CO[SiH3]

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.47
ALDH1A1 P00352 4/20 0.45
TDP1 Q9NUW8 1/20 0.45
TSHR P16473 2/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL614627 0.91 SMN1; SMN2 (0.53) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL5266072 0.90 TSHR (0.50) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL612291 0.88 SMN1; SMN2 (0.53) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL15610113 0.81 SMN1; SMN2 (0.53) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL613048 0.80 TSHR (0.57) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL1995127 0.80 SMN1; SMN2 (0.50) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL21516451 0.78 SMN1; SMN2 (0.49) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL27958377 0.78 TSHR (0.64) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL12035154 0.78 SMN1; SMN2 (0.55) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL5271678 0.77 TSHR (0.55) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2803699-B1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME BRIDGESTONE CORP (JP) 2018-09-12 EP disclosed
US-9623705-B2 Method for producing modified conjugated diene polymer/copolymer, modified conjugated diene polymer/copolymer, and rubber composition and tire using the same BRIDGESTONE CORPORATION (JP) 2017-04-18 US disclosed
US-9447208-B2 Rubber composition for tire, vulcanized rubber composition for tire, and tires using same BRIDGESTONE CORPORATION (JP) 2016-09-20 US disclosed
US-20140357804-A1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME BRIDGESTONE CORPORATION (JP) 2014-12-04 US disclosed
EP-2803699-A1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME Bridgestone Corporation (JP) 2014-11-19 EP disclosed
EP-2266819-B1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME BRIDGESTONE CORP (JP) 2013-11-06 EP disclosed
US-20110146877-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed
EP-2266819-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME Bridgestone Corporation (JP) 2010-12-29 EP disclosed