Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19973970 | 1.00 | CHRM3 (0.48) | CHRM3 | |
| SCHEMBL21189536 | 0.96 | CHRM3 (0.43) | CHRM3 | |
| SCHEMBL21189398 | 0.95 | CHRM3 (0.43) | CHRM3 | |
| SCHEMBL21189305 | 0.92 | MEN1 (0.40) | CHRM3 | |
| SCHEMBL21189212 | 0.90 | MEN1 (0.43) | CHRM3 | |
| SCHEMBL21189406 | 0.86 | CHRM2 (0.41) | CHRM3 | |
| SCHEMBL21189328 | 0.86 | POLB (0.38) | — | |
| SCHEMBL21189356 | 0.86 | POLB (0.38) | — | |
| SCHEMBL21189486 | 0.86 | NPC1 (0.45) | — | |
| SCHEMBL21189326 | 0.86 | NPC1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018052967-A1 | SUBSTITUTED CHROMANE-8-CARBOXAMIDE COMPOUNDS AND ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA, INC. (US) | 2018-03-22 | — | — | WO | disclosed |