Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GANAB | Q14697 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | GLB1 | P16278 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31348002 | 1.00 | GANAB (0.36) | GANABGBA1GLB1MGAMGAA | |
| SCHEMBL31348001 | 1.00 | GANAB (0.36) | GANABGBA1GLB1MGAMGAA | |
| SCHEMBL31348000 | 1.00 | GANAB (0.36) | GANABGBA1GLB1MGAMGAA | |
| SCHEMBL27245295 | 1.00 | GANAB (0.36) | GANABGBA1GLB1MGAMGAA | |
| SCHEMBL8069756 | 1.00 | GANAB (0.36) | GANABGBA1GLB1MGAMGAA | |
| SCHEMBL23058736 | 1.00 | GANAB (0.36) | GANABGBA1GLB1MGAMGAA | |
| SCHEMBL294003 | 1.00 | GANAB (0.36) | GANABGBA1GLB1MGAMGAA | |
| SCHEMBL8069758 | 1.00 | GANAB (0.36) | GANABGBA1GLB1MGAMGAA | |
| Hydrochloric Acid SCHEMBL4186715 | 0.97 | GBA1 (0.37) | GANABGBA1GLB1 | |
| SCHEMBL13077993 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210283278-A1 | CHIRAL CYCLEN COMPOUNDS AND THEIR USES | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2021-09-16 | — | — | US | claimed |
| US-11357873-B2 | Chiral cyclen compounds and their uses | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2022-06-14 | — | — | US | disclosed |
| US-20210283278-A1 | CHIRAL CYCLEN COMPOUNDS AND THEIR USES | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2021-09-16 | — | — | US | disclosed |
| EP-3515896-A1 | CHIRAL CYCLEN COMPOUNDS AND THEIR USES | The Hong Kong Polytechnic University (CN) | 2019-07-31 | — | — | EP | disclosed |
| WO-2018051197-A1 | CHIRAL CYCLEN COMPOUNDS AND THEIR USES | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2018-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11357873-B2 | Chiral cyclen compounds and their uses | DCTN3, DCTN1, CDK3 | GANAB 2966/4885GBA1 1406/4885GLB1 2571/4885 |
| US-20210283278-A1 | CHIRAL CYCLEN COMPOUNDS AND THEIR USES | DCTN3, DCTN1, CDK3 | GANAB 2966/4885GBA1 1406/4885GLB1 2571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.