SCHEMBL19975847

SCHEMBL19975847

Cc1cc(C)c(-n2ccnc2-c2cccc3nc(C)sc23)c(C)c1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.33
POLB P06746 1/20 0.33
CRHR1 P34998 1/20 0.32
MAPT P10636 1/20 0.31
FLT1 P17948 1/20 0.30
FLT4 P35916 1/20 0.30
KDR P35968 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12797936 0.76 FLT1 (0.42) MAPTFLT1FLT4KDR
SCHEMBL12797930 0.69 KDR (0.39) TP53POLBMAPTFLT1FLT4
SCHEMBL1316463 0.68 KDR (0.52) FLT1FLT4KDR
SCHEMBL12797931 0.68 FLT1 (0.49) POLBMAPTFLT1KDR
SCHEMBL19975846 0.68 GRM2 (0.35) MAPT
SCHEMBL13589306 0.67 KDM4E (0.33) TP53CRHR1FLT1FLT4KDR
SCHEMBL29877358 0.67 KDR (0.51) FLT1FLT4KDR
SCHEMBL29788366 0.67 KDR (0.51) FLT1FLT4KDR
SCHEMBL28848948 0.67 KDR (0.51) FLT1FLT4KDR
SCHEMBL29070232 0.67 KDR (0.51) FLT1FLT4KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2677561-B1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHTING DEVICE, AND DISPLAY DEVICE KONICA MINOLTA INC (JP) 2019-08-07 EP disclosed
US-9923154-B2 Organic electroluminescent element, lighting device, and display device Konica Minolta, Inc. (JP) 2018-03-20 US disclosed
US-9923154-B2 Organic electroluminescent element, lighting device, and display device Konica Minolta, Inc. (JP) 2018-03-20 US disclosed