Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.67 |
| ▸ | F2 | P00734 | 5/20 | 0.67 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.67 |
| ▸ | PDE4A | P27815 | 3/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218254 | 0.89 | F10 (0.69) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL19112113 | 0.88 | F10 (0.52) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL14629585 | 0.83 | F10 (0.74) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL15490610 | 0.83 | PDE4A (0.76) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL14240837 | 0.83 | F10 (0.66) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL541837 | 0.83 | F10 (0.77) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL19086424 | 0.82 | F10 (0.75) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL18365276 | 0.82 | F10 (0.85) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL28382402 | 0.82 | F10 (0.78) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL1997436 | 0.82 | F10 (0.75) | F10F2SLC29A1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920051-B2 | Key intermediates and impurities of the synthesis of apixaban: apixaban glycol esters | F.I.S.—Fabbrica Italiana Sintetici S.p.A. (IT) | 2018-03-20 | — | — | US | disclosed |