Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 9/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14889629 | 0.83 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4NPC1 | |
| SCHEMBL14889959 | 0.83 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4NPC1 | |
| SCHEMBL14900550 | 0.83 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4NPC1 | |
| SCHEMBL14890021 | 0.83 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4NPC1 | |
| SCHEMBL14889754 | 0.83 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4NPC1 | |
| SCHEMBL14890022 | 0.83 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4NPC1 | |
| SCHEMBL14760268 | 0.83 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4NPC1 | |
| SCHEMBL14760269 | 0.83 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4NPC1 | |
| SCHEMBL14889632 | 0.83 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4NPC1 | |
| SCHEMBL14889962 | 0.83 | S1PR5 (0.46) | S1PR5S1PR1S1PR3S1PR4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920028-B2 | Cationic lipid | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2018-03-20 | — | — | US | disclosed |