Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.79 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | ELANE | P08246 | 10/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17718432 | 0.90 | KDM1A (0.63) | KDM1AMAOBMAOAELANESMN1; SMN2 | |
| SCHEMBL16273286 | 0.88 | KDM1A (1.00) | KDM1AMAOBMAOAELANESMN1; SMN2 | |
| SCHEMBL31728921 | 0.88 | KDM1A (1.00) | KDM1AMAOBMAOAELANESMN1; SMN2 | |
| SCHEMBL17718444 | 0.88 | KDM1A (1.00) | KDM1AMAOBMAOAELANESMN1; SMN2 | |
| SCHEMBL16273305 | 0.87 | KDM1A (0.88) | KDM1AMAOBMAOAELANESMN1; SMN2 | |
| SCHEMBL18596569 | 0.85 | KDM1A (0.76) | KDM1AMAOBMAOASMN1; SMN2NPSR1 | |
| SCHEMBL15091433 | 0.85 | KDM1A (0.76) | KDM1AMAOBMAOASMN1; SMN2NPSR1 | |
| SCHEMBL15091431 | 0.85 | KDM1A (0.76) | KDM1AMAOBMAOASMN1; SMN2NPSR1 | |
| SCHEMBL15099831 | 0.85 | KDM1A (0.71) | KDM1AMAOBMAOASMN1; SMN2NPSR1 | |
| SCHEMBL16019177 | 0.85 | KDM1A (0.71) | KDM1AMAOBMAOASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9918983-B2 | Suicidal LSD1 inhibitors targeting SOX2-expressing cancer cells | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) | 2018-03-20 | — | — | US | disclosed |