SCHEMBL19976339

SCHEMBL19976339

Cc1c(N[C@@H](C)[C@@H](C)O)ccc(C#N)c1Cl

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AR P10275 13/20 0.56
PGR P06401 6/20 0.54
NR3C2 P08235 3/20 0.48
NR3C1 P04150 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12138411 1.00 AR (0.56) ARPGRNR3C2NR3C1
SCHEMBL12140330 0.83 AR (0.40) ARPGRNR3C2NR3C1
SCHEMBL16854099 0.83 AR (0.51) ARPGRNR3C2NR3C1
SCHEMBL1364405 0.82 AR (0.51) ARPGRNR3C2NR3C1
SCHEMBL1291460 0.82 AR (0.51) ARPGRNR3C2NR3C1
SCHEMBL12140386 0.82 AR (0.51) ARPGRNR3C2NR3C1
SCHEMBL12140529 0.82 AR (0.51) ARPGRNR3C2NR3C1
SCHEMBL12342293 0.82 AR (0.51) ARPGRNR3C2NR3C1
SCHEMBL1362970 0.82 AR (0.51) ARPGRNR3C2NR3C1
SCHEMBL12140365 0.82 AR (0.51) ARPGRNR3C2NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9920044-B2 Selective androgen receptor modulators RADIUS PHARMACEUTICALS, INC. (US) 2018-03-20 US disclosed