Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL769362 | 1.00 | KMT2A (0.56) | KMT2AMEN1L3MBTL1MAPTCYP3A4 | |
| SCHEMBL2692621 | 1.00 | KMT2A (0.56) | KMT2AMEN1L3MBTL1MAPTCYP3A4 | |
| SCHEMBL12754596 | 1.00 | KMT2A (0.56) | KMT2AMEN1L3MBTL1MAPTCYP3A4 | |
| SCHEMBL200621 | 1.00 | KMT2A (0.56) | KMT2AMEN1L3MBTL1MAPTCYP3A4 | |
| SCHEMBL3486991 | 1.00 | KMT2A (0.56) | KMT2AMEN1L3MBTL1MAPTCYP3A4 | |
| SCHEMBL10075962 | 1.00 | KMT2A (0.56) | KMT2AMEN1L3MBTL1MAPTCYP3A4 | |
| SCHEMBL20747758 | 0.91 | KMT2A (0.57) | KMT2AMEN1L3MBTL1MAPTCYP3A4 | |
| SCHEMBL468538 | 0.91 | KMT2A (0.57) | KMT2AMEN1L3MBTL1MAPTCYP3A4 | |
| SCHEMBL1294423 | 0.89 | MEN1 (0.52) | KMT2AMEN1L3MBTL1MAPTCYP3A4 | |
| SCHEMBL15508101 | 0.84 | KMT2A (0.56) | KMT2AMEN1L3MBTL1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919055-B2 | Sugar-linker-drug conjugates | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-20 | — | — | US | disclosed |