Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 6/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19062963 | 0.98 | PTPN1 (0.38) | PTPN1FOLH1HRH2HRH3CHRM1 | |
| SCHEMBL16252279 | 0.94 | PTPN1 (0.35) | PTPN1FOLH1HRH2HRH3CHRM1 | |
| SCHEMBL101648 | 0.88 | PTPN1 (0.36) | PTPN1FOLH1HRH2HRH3CHRM1 | |
| SCHEMBL101190 | 0.86 | PTPN1 (0.38) | PTPN1HRH2HRH3CHRM1CHRM3 | |
| SCHEMBL16252400 | 0.83 | PTPN1 (0.52) | PTPN1FOLH1HRH2HRH3CHRM1 | |
| SCHEMBL16784869 | 0.81 | PTPN1 (0.55) | PTPN1FOLH1HRH2HRH3CHRM1 | |
| SCHEMBL15500259 | 0.81 | HRH2 (0.30) | HRH2 | |
| SCHEMBL16252076 | 0.79 | PTPN1 (0.48) | PTPN1FOLH1HRH2HRH3CHRM1 | |
| SCHEMBL16561364 | 0.79 | — | — | |
| SCHEMBL17689344 | 0.79 | PTPN1 (0.40) | PTPN1FOLH1HRH2HRH3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920365-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-03-20 | — | — | US | disclosed |