Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 8/20 | 0.73 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | OXTR | P30559 | 1/20 | 0.68 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.68 |
| ▸ | CD81 | P60033 | 1/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.56 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.56 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.56 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.54 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.54 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.54 |
| ▸ | PTPRC | P08575 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976676 | 1.00 | F3 (0.73) | F3SIRT5CYP3A4MAPK1OXTR | |
| SCHEMBL17133001 | 1.00 | F3 (0.73) | F3SIRT5CYP3A4MAPK1OXTR | |
| SCHEMBL17132986 | 1.00 | F3 (0.73) | F3SIRT5CYP3A4MAPK1OXTR | |
| SCHEMBL17132983 | 0.90 | F3 (0.66) | F3SIRT5CYP3A4MAPK1OXTR | |
| SCHEMBL19976704 | 0.90 | F3 (0.59) | F3SIRT5CYP3A4MAPK1OXTR | |
| SCHEMBL17133043 | 0.88 | F3 (0.73) | F3SIRT5PTPN1EGLN2EGLN1 | |
| SCHEMBL19976668 | 0.88 | F3 (0.73) | F3SIRT5PTPN1EGLN2EGLN1 | |
| SCHEMBL17030493 | 0.88 | F3 (0.73) | F3SIRT5PTPN1EGLN2EGLN1 | |
| SCHEMBL19976677 | 0.88 | F3 (0.73) | F3SIRT5PTPN1EGLN2EGLN1 | |
| SCHEMBL17133059 | 0.85 | F3 (1.00) | F3SIRT5CYP3A4MAPK1OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920088-B2 | Triterpene derivative and its anti-influenza use | University of Macao (CN) | 2018-03-20 | — | — | US | disclosed |