Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.34 |
| ▸ | KIT | P10721 | 3/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19362621 | 0.80 | RET (0.32) | KITKDR | |
| SCHEMBL16682137 | 0.74 | GSK3B (0.50) | GSK3BHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL18556896 | 0.70 | GSK3B (0.52) | GSK3BHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL18556955 | 0.70 | GSK3B (0.53) | GSK3BHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL19976814 | 0.70 | MAPT (0.47) | GSK3BFGFR1DDR2KITFLT3 | |
| SCHEMBL19976874 | 0.67 | GSK3B (0.39) | GSK3BFGFR1DDR2KITFLT3 | |
| SCHEMBL19976725 | 0.65 | GSK3B (0.52) | GSK3BHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL16675965 | 0.65 | GSK3B (0.47) | GSK3BHDAC1HDAC2HDAC8ALDH1A1 | |
| SCHEMBL16675962 | 0.64 | GSK3B (0.40) | GSK3BCYP1A2 | |
| SCHEMBL19976754 | 0.63 | HDAC6 (0.52) | GSK3BHDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920012-B2 | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |