Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22869167 | 0.81 | — | — | |
| SCHEMBL20940632 | 0.81 | PTPN1 (0.34) | CHUK | |
| SCHEMBL12658526 | 0.80 | CDK2 (0.52) | CHUKCCNA2CDK2CCNA1 | |
| SCHEMBL10485447 | 0.72 | CHUK (0.37) | CHUK | |
| SCHEMBL19978936 | 0.71 | PDPK1 (0.38) | — | |
| SCHEMBL22333846 | 0.70 | CHUK (0.36) | CHUK | |
| SCHEMBL14216356 | 0.68 | POLB (0.37) | CCNA2CDK2CCNA1 | |
| SCHEMBL22700395 | 0.68 | CCNA2 (0.35) | CCNA2CDK2CCNA1 | |
| SCHEMBL13828374 | 0.68 | MEN1 (0.53) | CHUKCCNA2CDK2CCNA1 | |
| SCHEMBL10485026 | 0.68 | CHUK (0.40) | CHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018049534-A1 | NUCLEOSIDE AND NUCLEOTIDE ANALOGUES BEARING A QUATERNARY ALL-CARBON STEREOGENIC CENTER AT THE 2' POSITION AND METHODS OF USE AS A CARDIOPROTECTIVE AGENT | LCB PHARMA INC. (CA) | 2018-03-22 | — | — | WO | disclosed |