Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | RAC2 | P15153 | 1/20 | 0.31 |
| ▸ | RAC3 | P60763 | 1/20 | 0.31 |
| ▸ | CDC42 | P60953 | 1/20 | 0.31 |
| ▸ | RAC1 | P63000 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19009379 | 0.98 | ATM (0.40) | ATML3MBTL1KDM4EPIM3TSPO | |
| SCHEMBL1687716 | 0.98 | ATM (0.40) | ATML3MBTL1KDM4EPIM3TSPO | |
| SCHEMBL19009387 | 0.98 | ATM (0.40) | ATML3MBTL1KDM4EPIM3TSPO | |
| SCHEMBL17998188 | 0.98 | KDM4E (0.40) | ATML3MBTL1KDM4EPIM3TSPO | |
| SCHEMBL14867996 | 0.98 | PIM3 (0.37) | ATML3MBTL1KDM4EPIM3TSPO | |
| SCHEMBL25619055 | 0.97 | KDM4E (0.38) | ATML3MBTL1KDM4EPIM3TSPO | |
| SCHEMBL18201555 | 0.96 | ATM (0.41) | ATML3MBTL1KDM4EPIM3TSPO | |
| SCHEMBL14868017 | 0.96 | PIM3 (0.38) | ATML3MBTL1KDM4EPIM3TSPO | |
| SCHEMBL14212277 | 0.96 | PIM3 (0.38) | ATML3MBTL1KDM4EPIM3TSPO | |
| SCHEMBL24301385 | 0.95 | ATM (0.45) | ATML3MBTL1KDM4EPIM3TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512848-B1 | COMPOUNDS WITH CARBAZOLE STRUCTURES | MERCK PATENT GMBH (DE) | 2020-11-18 | — | — | EP | disclosed |
| WO-2018050584-A1 | COMPOUNDS WITH SPIROBIFLUORENE-STRUCTURES | MERCK PATENT GMBH (DE) | 2018-03-22 | — | — | WO | disclosed |