Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15893683 | 0.88 | SYK (0.49) | SYKMAPTIDO1HTTL3MBTL1 | |
| SCHEMBL25376272 | 0.83 | HTT (0.50) | SYKMAPTIDO1HTTL3MBTL1 | |
| SCHEMBL24897148 | 0.83 | HTT (0.50) | SYKMAPTIDO1HTTL3MBTL1 | |
| SCHEMBL1455284 | 0.83 | SYK (0.51) | SYKMAPTIDO1HTTL3MBTL1 | |
| SCHEMBL16789588 | 0.82 | HTT (0.58) | SYKMAPTIDO1HTTL3MBTL1 | |
| SCHEMBL25463464 | 0.82 | SYK (0.48) | SYKMAPTIDO1HTTL3MBTL1 | |
| SCHEMBL7431128 | 0.82 | HTT (0.60) | SYKMAPTIDO1HTTL3MBTL1 | |
| SCHEMBL18429584 | 0.82 | SYK (0.50) | SYKMAPTIDO1HTTL3MBTL1 | |
| SCHEMBL4927806 | 0.81 | HTT (0.51) | SYKMAPTHTTL3MBTL1LMNA | |
| SCHEMBL4924340 | 0.81 | HTT (0.56) | SYKMAPTIDO1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751141-B1 | STABLE PEPTIDE-BASED PACE4 INHIBITORS | SOCPRA SCIENCES SANTE ET HUMAINES S E C (CA) | 2018-03-21 | — | — | EP | disclosed |