Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9984471 | 0.94 | BTK (0.40) | BTK | |
| SCHEMBL2490951 | 0.94 | BTK (0.40) | BTK | |
| SCHEMBL9985016 | 0.94 | BTK (0.40) | BTK | |
| SCHEMBL2489760 | 0.88 | BTK (0.40) | BTK | |
| SCHEMBL9984473 | 0.88 | BTK (0.40) | BTK | |
| SCHEMBL9985937 | 0.88 | BTK (0.40) | BTK | |
| SCHEMBL12026174 | 0.86 | BTK (0.39) | BTK | |
| SCHEMBL2490213 | 0.86 | BTK (0.39) | BTK | |
| SCHEMBL9984571 | 0.86 | BTK (0.39) | BTK | |
| SCHEMBL9984635 | 0.82 | BTK (0.41) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2365970-B1 | PYRIDAZINONES AND THEIR USE AS BTK INHIBITORS | GILEAD CONNECTICUT INC (US) | 2018-03-21 | — | — | EP | disclosed |