Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 11/20 | 0.49 |
| ▸ | FGR | P09769 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | TEC | P42680 | 1/20 | 0.44 |
| ▸ | BMX | P51813 | 1/20 | 0.44 |
| ▸ | CCND3 | P30281 | 3/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.37 |
| ▸ | CCNK | O75909 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 2/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAP4K1 | Q92918 | 5/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9984996 | 0.88 | BTK (0.61) | BTKFGRSRCTECBMX | |
| SCHEMBL2492024 | 0.73 | BTK (0.56) | BTKFGRSRCTECBMX | |
| SCHEMBL2464982 | 0.72 | BTK (0.49) | BTKFGRSRCTECBMX | |
| SCHEMBL2462583 | 0.72 | BTK (0.63) | BTKFGRSRCTECBMX | |
| SCHEMBL2492037 | 0.72 | BTK (0.59) | BTKFGRSRCTECBMX | |
| SCHEMBL2491658 | 0.71 | BTK (0.64) | BTKFGRSRCTECBMX | |
| SCHEMBL19981677 | 0.71 | BTK (0.60) | BTKFGRSRCTECBMX | |
| SCHEMBL1423507 | 0.70 | BTK (0.51) | BTKFGRTECBMX | |
| SCHEMBL2488701 | 0.70 | BTK (0.70) | BTKFGRSRCTECBMX | |
| SCHEMBL13626138 | 0.69 | BTK (0.51) | BTKFGRTECBMX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2365970-B1 | PYRIDAZINONES AND THEIR USE AS BTK INHIBITORS | GILEAD CONNECTICUT INC (US) | 2018-03-21 | — | — | EP | disclosed |