Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9984295 | 0.81 | BTK (0.54) | BTK | |
| SCHEMBL9985163 | 0.73 | BTK (0.52) | BTK | |
| SCHEMBL2490369 | 0.70 | BTK (0.66) | BTK | |
| SCHEMBL2495522 | 0.70 | BTK (0.66) | BTK | |
| SCHEMBL2490998 | 0.70 | BTK (0.66) | BTK | |
| SCHEMBL2528678 | 0.69 | BTK (0.69) | BTK | |
| SCHEMBL12025683 | 0.68 | BTK (0.76) | BTK | |
| SCHEMBL9984057 | 0.68 | BTK (0.36) | BTK | |
| SCHEMBL19981806 | 0.67 | BTK (0.55) | BTK | |
| SCHEMBL2494310 | 0.66 | BTK (0.52) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2365970-B1 | PYRIDAZINONES AND THEIR USE AS BTK INHIBITORS | GILEAD CONNECTICUT INC (US) | 2018-03-21 | — | — | EP | disclosed |