⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22856027 | 0.83 | — | — | |
| SCHEMBL22540837 | 0.82 | — | — | |
| SCHEMBL25829096 | 0.82 | — | — | |
| SCHEMBL20825070 | 0.81 | — | — | |
| SCHEMBL24682103 | 0.81 | — | — | |
| SCHEMBL13859963 | 0.81 | — | — | |
| SCHEMBL19966726 | 0.79 | — | — | |
| SCHEMBL20159939 | 0.79 | — | — | |
| SCHEMBL1109085 | 0.79 | — | — | |
| SCHEMBL24346059 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458460-B1 | IMIDAZOLES AS HISTONE DEMETHYLASE INHIBITORS | ST EUROPEO DI ONCOLOGIA S R L (IT) | 2020-12-09 | — | — | EP | disclosed |
| US-20180079757-A1 | BACTERIAL TOPOISOMERASE I INHIBITORS WITH ANTIBACTERIAL ACTIVITY | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES | 2018-03-22 | — | — | US | disclosed |