Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.72 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.72 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.66 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5983223 | 1.00 | PNP (0.72) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL7655056 | 1.00 | PNP (0.72) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL7655065 | 1.00 | PNP (0.72) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL5983227 | 1.00 | PNP (0.72) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL17921081 | 1.00 | PNP (0.72) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL4072041 | 0.89 | PNP (0.68) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL13923997 | 0.89 | PNP (0.68) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL8826240 | 0.88 | PNP (0.56) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL5982240 | 0.88 | PNP (0.58) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL5982228 | 0.88 | PNP (0.58) | PNPLMNATP53HTTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516637-B1 | THERMOSTABLE BIOCATALYST COMBINATION FOR NUCLEOSIDE SYNTHESIS | PLASMIA BIOTECH S L (ES) | 2016-04-20 | — | — | EP | disclosed |
| US-8759034-B2 | Thermostable biocatalyst combination for nucleoside synthesis | PLASMIA BIOTECH, S.L. (ES) | 2014-06-24 | — | — | US | disclosed |
| US-20130337547-A1 | THERMOSTABLE BIOCATALYST COMBINATION FOR NUCLEOSIDE SYNTHESIS | BRILL ENGINES, S.L. (ES) | 2013-12-19 | — | — | US | disclosed |
| US-8512997-B2 | Thermostable biocatalyst combination for nucleoside synthesis | PLASMIA BIOTECH, S.L. (ES) | 2013-08-20 | — | — | US | disclosed |
| EP-2516637-A1 | THERMOSTABLE BIOCATALYST COMBINATION FOR NUCLEOSIDE SYNTHESIS | Plasmia Biotech, S.L. (ES) | 2012-10-31 | — | — | EP | disclosed |
| US-20120264175-A1 | THERMOSTABLE BIOCATALYST COMBINATION FOR NUCLEOSIDE SYNTHESIS | BRILL ENGINES, S.L. (ES) | 2012-10-18 | — | — | US | disclosed |
| WO-2011076894-A1 | THERMOSTABLE BIOCATALYST COMBINATION FOR NUCLEOSIDE SYNTHESIS | INSTITUT UNIV. DE CIÈNCIA I TECNOLOGIA, S.A. (ES) | 2011-06-30 | — | — | WO | disclosed |
| EP-2338985-A1 | Thermostable biocatalyst combination for nucleoside synthesis | Institut Univ. de Ciència i Tecnologia, s.a. (ES) | 2011-06-29 | — | — | EP | disclosed |