Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19974957 | 0.83 | MAPT (0.54) | MEN1KMT2AMAPTTAAR1TAS1R3 | |
| SCHEMBL30062957 | 0.83 | MAPT (0.54) | MEN1KMT2AMAPTTAAR1TAS1R3 | |
| SCHEMBL29357750 | 0.80 | CCNK (0.53) | MEN1KMT2AMAPTTAAR1TAS1R3 | |
| SCHEMBL7697763 | 0.80 | CCNK (0.53) | MEN1KMT2AMAPTTAAR1TAS1R3 | |
| SCHEMBL13623452 | 0.76 | ESR1 (0.50) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL29390456 | 0.76 | ESR1 (0.50) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8221038 | 0.75 | NOTUM (0.63) | TAS1R3TAS1R1TAS1R2ESR1ESR2 | |
| SCHEMBL10802449 | 0.72 | HDAC8 (0.50) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2821470 | 0.71 | ESR1 (0.76) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL29989790 | 0.71 | ESR1 (0.76) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050631-A1 | ANTIVIRAL COMPOUNDS | HAPLOGEN GMBH (AT) | 2018-03-22 | — | — | WO | disclosed |