Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19975392 | 0.77 | EPHX1 (0.59) | EPHX1CTSKCTSLCTSBCA12 | |
| SCHEMBL11178040 | 0.76 | EPHX1 (0.58) | EPHX1CTSKCTSLCTSBCA12 | |
| SCHEMBL19974743 | 0.75 | EPHX1 (0.56) | EPHX1CTSKCTSLCTSBCA12 | |
| SCHEMBL11171103 | 0.74 | EPHX1 (0.56) | EPHX1CTSKCTSLCTSBCA12 | |
| SCHEMBL11174517 | 0.73 | EPHX1 (0.55) | EPHX1CTSKCTSLCTSBCA12 | |
| SCHEMBL19974693 | 0.73 | EPHX1 (0.54) | EPHX1CTSKCTSLCTSBCA12 | |
| SCHEMBL19975076 | 0.71 | EPHX1 (0.52) | EPHX1CTSKCTSLCTSBCA12 | |
| SCHEMBL21176165 | 0.71 | EPHX1 (0.51) | EPHX1CTSKCTSLCTSBCA12 | |
| SCHEMBL24383485 | 0.70 | EPHX1 (1.00) | EPHX1CTSKCTSLCTSBCA12 | |
| SCHEMBL21229787 | 0.70 | EPHX1 (1.00) | EPHX1CTSKCTSLCTSBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050631-A1 | ANTIVIRAL COMPOUNDS | HAPLOGEN GMBH (AT) | 2018-03-22 | — | — | WO | disclosed |