Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSH | P09668 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21153429 | 1.00 | CTSH (0.42) | CTSHCTSKMAOAMAOB | |
| SCHEMBL19983056 | 1.00 | CTSH (0.42) | CTSHCTSKMAOAMAOB | |
| SCHEMBL19983116 | 0.85 | MEN1 (0.34) | — | |
| SCHEMBL21152646 | 0.85 | FOLH1 (0.35) | — | |
| SCHEMBL23023504 | 0.82 | CA12 (0.54) | — | |
| SCHEMBL21152642 | 0.82 | CA12 (0.54) | — | |
| SCHEMBL23023432 | 0.82 | CTSH (0.49) | CTSHCTSK | |
| SCHEMBL19983025 | 0.82 | CTSH (0.46) | CTSHCTSK | |
| SCHEMBL19983289 | 0.80 | FOLH1 (0.47) | CTSHCTSK | |
| SCHEMBL25659866 | 0.79 | FOLH1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053353-A1 | KETONE INHIBITORS OF LYSINE GINGIPAIN | Cortexyme, Inc. (US) | 2018-03-22 | — | — | WO | disclosed |