Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.61 |
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 4/20 | 0.61 |
| ▸ | CA9 | Q16790 | 4/20 | 0.61 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21153279 | 1.00 | CA12 (0.61) | CA12CA1CA2CA9PLG | |
| SCHEMBL21152627 | 1.00 | CA12 (0.61) | CA12CA1CA2CA9PLG | |
| SCHEMBL19982967 | 1.00 | CA12 (0.61) | CA12CA1CA2CA9PLG | |
| SCHEMBL19983271 | 1.00 | CA12 (0.61) | CA12CA1CA2CA9PLG | |
| SCHEMBL30716860 | 1.00 | CA12 (0.61) | CA12CA1CA2CA9PLG | |
| SCHEMBL23023452 | 0.95 | CA12 (0.55) | CA12CA1CA2CA9PLG | |
| SCHEMBL22292196 | 0.95 | CA12 (0.55) | CA12CA1CA2CA9PLG | |
| SCHEMBL21152460 | 0.95 | CA12 (0.55) | CA12CA1CA2CA9PLG | |
| SCHEMBL22292204 | 0.95 | CA12 (0.55) | CA12CA1CA2CA9PLG | |
| SCHEMBL21152626 | 0.95 | CA12 (0.55) | CA12CA1CA2CA9PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053353-A1 | KETONE INHIBITORS OF LYSINE GINGIPAIN | Cortexyme, Inc. (US) | 2018-03-22 | — | — | WO | disclosed |