Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 4/20 | 1.00 |
| ▸ | NNMT | P40261 | 6/20 | 0.69 |
| ▸ | NSD2 | O96028 | 6/20 | 0.69 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.69 |
| ▸ | PCMT1 | P22061 | 2/20 | 0.69 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.69 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.69 |
| ▸ | SETD2 | Q9BYW2 | 2/20 | 0.69 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.69 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.69 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.69 |
| ▸ | RNMT | O43148 | 1/20 | 0.69 |
| ▸ | INMT | O95050 | 1/20 | 0.69 |
| ▸ | TPMT | P51580 | 1/20 | 0.69 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.69 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.69 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.69 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.69 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.69 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14906024 | 1.00 | CARM1 (1.00) | CARM1NNMTNSD2SETD7PCMT1 | |
| SCHEMBL16156831 | 1.00 | CARM1 (1.00) | CARM1NNMTNSD2SETD7PCMT1 | |
| SCHEMBL19983490 | 0.90 | CARM1 (0.82) | CARM1NNMTNSD2SETD7PCMT1 | |
| SCHEMBL19983537 | 0.88 | CARM1 (0.85) | CARM1NNMTNSD2SETD7PCMT1 | |
| SCHEMBL14905982 | 0.87 | CARM1 (0.77) | CARM1NNMTNSD2SETD7PCMT1 | |
| SCHEMBL16154106 | 0.87 | CARM1 (0.77) | CARM1NNMTNSD2SETD7PCMT1 | |
| SCHEMBL26453664 | 0.87 | CARM1 (0.76) | CARM1NNMTNSD2SETD7PCMT1 | |
| SCHEMBL19983600 | 0.86 | CARM1 (0.76) | CARM1NNMTNSD2SETD7PCMT1 | |
| SCHEMBL21342596 | 0.86 | CARM1 (1.00) | CARM1NNMTNSD2SETD7PCMT1 | |
| SCHEMBL21343829 | 0.86 | CARM1 (1.00) | CARM1NNMTNSD2SETD7PCMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043645-B2 | Adenosine analogs as methyltransferase inhibitors for treating cancer | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2024-07-23 | — | — | US | disclosed |
| US-20230135822-A1 | ADENOSINE ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2023-05-04 | — | — | US | disclosed |
| US-10730903-B2 | Adenosine analogs as methyltransferase inhibitors for treating cancer | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2020-08-04 | — | — | US | disclosed |
| US-20190276488-A1 | ADENOSINE ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2019-09-12 | — | — | US | disclosed |
| WO-2018053313-A1 | ADENOSINE ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2018-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190276488-A1 | ADENOSINE ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | DIMT1, TPMT, MTAP | CARM1 62/4885NNMT 6/4885NSD2 188/4885 |
| US-12043645-B2 | Adenosine analogs as methyltransferase inhibitors for treating cancer | DIMT1, TPMT, MTAP | CARM1 62/4885NNMT 6/4885NSD2 188/4885 |
| US-20230135822-A1 | ADENOSINE ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | DIMT1, TPMT, MTAP | CARM1 62/4885NNMT 6/4885NSD2 188/4885 |
| US-10730903-B2 | Adenosine analogs as methyltransferase inhibitors for treating cancer | DIMT1, TPMT, MTAP | CARM1 62/4885NNMT 6/4885NSD2 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.