Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.85 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.85 |
| ▸ | TK1 | P04183 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | ALB | P02768 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | POLA1 | P09884 | 1/20 | 0.65 |
| ▸ | POLD1 | P28340 | 1/20 | 0.65 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28454169 | 1.00 | ABCG2 (0.85) | ABCG2ABCB1TK1LMNATSHR | |
| SCHEMBL14598130 | 1.00 | ABCG2 (0.85) | ABCG2ABCB1TK1LMNATSHR | |
| SCHEMBL28898454 | 0.96 | ABCG2 (0.91) | ABCG2ABCB1TK1LMNATSHR | |
| SCHEMBL28445739 | 0.95 | ABCG2 (0.92) | ABCG2ABCB1TK1LMNATSHR | |
| SCHEMBL28450305 | 0.95 | ABCG2 (0.89) | ABCG2ABCB1TK1LMNATSHR | |
| SCHEMBL28445736 | 0.93 | ABCG2 (0.98) | ABCG2ABCB1TK1LMNATSHR | |
| SCHEMBL28456159 | 0.93 | ABCG2 (0.95) | ABCG2ABCB1TK1LMNATSHR | |
| SCHEMBL19983496 | 0.91 | ABCG2 (0.82) | ABCG2ABCB1TK1LMNATSHR | |
| SCHEMBL13609904 | 0.91 | ABCG2 (0.81) | ABCG2ABCB1TK1LMNATSHR | |
| SCHEMBL13781383 | 0.90 | ABCG2 (0.89) | ABCG2ABCB1TK1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2175863-B1 | SUBSTITUTED NUCLEOSIDE DERIVATIVES WITH ANTIVIRAL AND ANTIMICROBIAL PROPERTIES | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2018-03-21 | — | — | EP | disclosed |