Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15783775 | 0.90 | CHRM3 (0.60) | CHRM3KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL19984429 | 0.90 | CHRM3 (0.62) | CHRM3KMT2ASMN1; SMN2MEN1RAB9A | |
| SCHEMBL20373866 | 0.90 | CHRM3 (0.62) | CHRM3KMT2ASMN1; SMN2MEN1RAB9A | |
| SCHEMBL15768180 | 0.87 | CHRM3 (0.63) | CHRM3KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL14166011 | 0.87 | CHRM3 (0.63) | CHRM3KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL15777842 | 0.85 | SMPD1 (0.55) | CHRM3KMT2ASMN1; SMN2MEN1MAOB | |
| SCHEMBL15777839 | 0.85 | SMPD1 (0.55) | CHRM3KMT2ASMN1; SMN2MEN1MAOB | |
| SCHEMBL14240960 | 0.85 | KMT2A (0.58) | CHRM3KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL14240961 | 0.84 | KMT2A (0.55) | CHRM3KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL15783778 | 0.84 | KMT2A (0.57) | CHRM3KMT2ASMN1; SMN2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345904-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2020-07-29 | — | — | EP | disclosed |
| EP-2928889-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2018-03-21 | — | — | EP | disclosed |