SCHEMBL1998457

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2003083	0.91	MAPT (0.55)	KDM4ERAB9AMAPTSMN1; SMN2TP53
	SCHEMBL1997619	0.91	MAPT (0.57)	KDM4EMAPTSMN1; SMN2TP53RXFP1
	SCHEMBL2000452	0.90	MAPT (0.56)	KDM4ERAB9ANPC1MAPTSMN1; SMN2
	SCHEMBL2002931	0.88	GFER (0.59)	RAB9ANPC1MAPTSMN1; SMN2TP53
	SCHEMBL1999173	0.86	KDM4E (0.55)	KDM4ERAB9ANPC1MAPK1PPARG
	SCHEMBL1996888	0.83	MAPT (0.52)	KDM4ERAB9ANPC1MAPK1PPARG
	SCHEMBL12567437	0.82	CNR1 (0.54)	KDM4ERAB9ANPC1MAPK1PPARG
	SCHEMBL1995486	0.82	KDM4E (0.55)	KDM4ERAB9ANPC1MAPK1PPARG
	SCHEMBL2000108	0.78	CNR2 (0.56)	KDM4ERAB9ANPC1MAPK1PPARG
	SCHEMBL1996659	0.78	MAPT (0.49)	RAB9AMAPTSMN1; SMN2TP53RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.