Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 13/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984573 | 1.00 | EGLN1 (0.39) | EGLN1KLKB1RAB9APOLBALDH1A1 | |
| SCHEMBL19984760 | 1.00 | EGLN1 (0.39) | EGLN1KLKB1RAB9APOLBALDH1A1 | |
| SCHEMBL24221965 | 0.87 | EGLN1 (0.38) | EGLN1KLKB1ALDH1A1MAPTKDM4E | |
| SCHEMBL21291454 | 0.87 | EGLN1 (0.38) | EGLN1KLKB1ALDH1A1MAPTKDM4E | |
| SCHEMBL21291411 | 0.87 | EGLN1 (0.38) | EGLN1KLKB1ALDH1A1MAPTKDM4E | |
| SCHEMBL21291452 | 0.86 | EGLN1 (0.38) | EGLN1KLKB1ALDH1A1MAPTKDM4E | |
| SCHEMBL19984744 | 0.85 | EGLN1 (0.39) | EGLN1KLKB1ALDH1A1MAPTKDM4E | |
| SCHEMBL21291446 | 0.84 | EGLN1 (0.38) | EGLN1KLKB1ALDH1A1MAPTKDM4E | |
| SCHEMBL19984638 | 0.81 | EGLN1 (0.39) | EGLN1KLKB1ALDH1A1MAPTKDM4E | |
| SCHEMBL21291409 | 0.79 | EGLN1 (0.42) | EGLN1KLKB1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053157-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2018-03-22 | — | — | WO | disclosed |