Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984785 | 1.00 | KMT2A (0.47) | KMT2AMEN1ALDH1A1NPC1LMNA | |
| SCHEMBL4229005 | 0.89 | KMT2A (0.55) | KMT2AMEN1ALDH1A1NPC1LMNA | |
| SCHEMBL4229009 | 0.89 | KMT2A (0.55) | KMT2AMEN1ALDH1A1NPC1LMNA | |
| SCHEMBL14599774 | 0.86 | KMT2A (0.52) | KMT2AMEN1ALDH1A1NPC1LMNA | |
| SCHEMBL14599775 | 0.86 | KMT2A (0.52) | KMT2AMEN1ALDH1A1NPC1LMNA | |
| SCHEMBL29625036 | 0.80 | KMT2A (0.42) | KMT2AMEN1UCHL1BACE1 | |
| SCHEMBL4220901 | 0.80 | KMT2A (0.46) | KMT2AMEN1ALDH1A1NPC1LMNA | |
| SCHEMBL4220908 | 0.80 | KMT2A (0.46) | KMT2AMEN1ALDH1A1NPC1LMNA | |
| SCHEMBL5035720 | 0.79 | PRCP (0.48) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL22892446 | 0.79 | MEN1 (0.50) | KMT2AMEN1ALDH1A1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051255-A1 | CYCLIC SUBSTITUTED-1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |