Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.36 |
| ▸ | HTR2A | P28223 | 6/20 | 0.36 |
| ▸ | HTR2B | P41595 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19985303 | 1.00 | HTR2C (0.36) | HTR2CHTR2AHTR2BGAAMAPT | |
| SCHEMBL19985293 | 1.00 | HTR2C (0.36) | HTR2CHTR2AHTR2BGAAMAPT | |
| SCHEMBL19985294 | 0.99 | HTR2C (0.36) | HTR2CHTR2AHTR2BGAAMAPT | |
| SCHEMBL19985272 | 0.96 | HTR2C (0.37) | HTR2CHTR2AHTR2BGAAMAPT | |
| SCHEMBL8962834 | 0.93 | HTR2C (0.32) | HTR2CHTR2AHTR2BGAAMAPT | |
| SCHEMBL8963378 | 0.93 | HTR2C (0.32) | HTR2CHTR2AHTR2BGAAMAPT | |
| SCHEMBL8962924 | 0.93 | HTR2C (0.32) | HTR2CHTR2AHTR2BGAAMAPT | |
| SCHEMBL19985620 | 0.93 | HTR2C (0.35) | HTR2CHTR2AHTR2BGAAMAPT | |
| SCHEMBL19985612 | 0.93 | HTR2C (0.35) | HTR2CHTR2AHTR2BGAAMAPT | |
| SCHEMBL19985625 | 0.93 | HTR2C (0.35) | HTR2CHTR2AHTR2BGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079959-A1 | LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY | DIC CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |
| US-20180079959-A1 | LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY | DIC CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |