SCHEMBL19985664

SCHEMBL19985664

C=C(C)Oc1ccc(-c2ccc(C(=O)Oc3ccc(C(=O)OCCOC(=O)C(=C)C)cc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.47
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
HTT P42858 1/20 0.47
MAPT P10636 9/20 0.43
KMT2A Q03164 4/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
ELANE P08246 1/20 0.43
LMNA P02545 4/20 0.42
KDM4E B2RXH2 1/20 0.42
HSP90AA1 P07900 1/20 0.42
HSD17B10 Q99714 2/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
PRSS1 P07477 1/20 0.40
ACR P10323 1/20 0.40
NPC1 O15118 2/20 0.39
RAB9A P51151 1/20 0.39
THRB P10828 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17481306 0.93 ELANE (0.50) TDP1POLBAPEX1HTTMAPT
SCHEMBL18418414 0.93 ELANE (0.50) TDP1POLBAPEX1HTTMAPT
SCHEMBL21422396 0.92 POLB (0.54) TDP1POLBAPEX1HTTMAPT
SCHEMBL16340780 0.91 ELANE (0.52) TDP1POLBAPEX1HTTMAPT
SCHEMBL16351932 0.91 ELANE (0.52) TDP1POLBAPEX1HTTMAPT
SCHEMBL21279892 0.89 KMT2A (0.47) TDP1POLBAPEX1HTTMAPT
SCHEMBL19651328 0.88 POLB (0.58) TDP1POLBAPEX1HTTMAPT
SCHEMBL14346714 0.88 POLB (0.52) TDP1POLBAPEX1HTTMAPT
SCHEMBL16351937 0.87 TDP1 (0.50) TDP1POLBAPEX1HTTMAPT
SCHEMBL16351931 0.87 TDP1 (0.50) TDP1POLBAPEX1HTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10338436-B2 Method of manufacturing curved liquid crystal display device and curved liquid crystal display device SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-02 US disclosed
US-20180081243-A1 METHOD OF MANUFACTURING CURVED LIQUID CRYSTAL DISPLAY DEVICE AND CURVED LIQUID CRYSTAL DISPLAY DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-22 US disclosed