SCHEMBL19985983

SCHEMBL19985983

c1ccc(-c2nc(-n3c4ccccc4c4c5c6ccccc6c6ccccc6c5c5c6ccccc6sc5c43)nc3c2sc2ccccc23)cc1

nearest known ligand 0.31

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TNKS O95271 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
HRH4 Q9H3N8 1/20 0.31
EGLN1 Q9GZT9 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
RECQL P46063 1/20 0.30
MMP14 P50281 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19986187 0.98 TNKS (0.32) TNKSTNKS2
SCHEMBL17297540 0.94 TNKS (0.32) TNKSTNKS2HRH4EGLN1MEN1
SCHEMBL19985984 0.93 LIMK1 (0.30)
SCHEMBL17297533 0.93 TNKS (0.33) TNKSTNKS2HRH4EGLN1
SCHEMBL18687758 0.93 PIM1 (0.31) TNKSTNKS2HRH4EGLN1
SCHEMBL19046689 0.92 TNKS (0.32) TNKSTNKS2HRH4MEN1LMNA
SCHEMBL19998017 0.90 KDM4E (0.33) TNKSTNKS2HRH4LMNAMAPT
SCHEMBL17305787 0.90 TNKS (0.32) TNKSTNKS2HRH4EGLN1MEN1
SCHEMBL17305678 0.89 PIM1 (0.31) TNKSTNKS2HRH4EGLN1MEN1
SCHEMBL17297372 0.89 TNKS (0.31) TNKSTNKS2HRH4EGLN1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed