SCHEMBL19986185

SCHEMBL19986185

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-n4c5ccccc5c5c6c7ccccc7c7ccccc7c6c6c7ccccc7sc6c54)c3)n2)cc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.34
RXFP1 Q9HBX9 2/20 0.34
TP53 P04637 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30
ABCG2 Q9UNQ0 3/20 0.30
LMNA P02545 1/20 0.30
RAB9A P51151 1/20 0.30
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
KMT2A Q03164 1/20 0.30
TNKS O95271 1/20 0.30
TNKS2 Q9H2K2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18505626 0.94 MAPT (0.34) MAPTRXFP1TP53KDM4EATM
SCHEMBL17405689 0.94 MAPT (0.34) MAPTRXFP1TP53KDM4EATM
SCHEMBL17405401 0.94 MAPT (0.34) MAPTRXFP1TP53KDM4EATM
SCHEMBL19986037 0.94 MAPT (0.32) MAPTRXFP1TP53
SCHEMBL19985955 0.94 MAPT (0.34) MAPTRXFP1TP53KDM4ELMNA
SCHEMBL17406027 0.94 MAPT (0.34) MAPTRXFP1TP53KDM4EATM
SCHEMBL17405802 0.94 MAPT (0.34) MAPTRXFP1TP53KDM4EATM
SCHEMBL17405489 0.92 MAPT (0.34) MAPTRXFP1TP53KDM4EATM
SCHEMBL17405748 0.92 MAPT (0.34) MAPTRXFP1TP53KDM4EATM
SCHEMBL17405833 0.91 MAPT (0.35) MAPTRXFP1TP53KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed