SCHEMBL19986189

SCHEMBL19986189

c1ccc(-c2cccc(-c3nc(-n4c5ccccc5c5c6c7ccccc7c7ccccc7c6c6c7ccccc7sc6c54)nc4c3oc3ccccc34)c2)cc1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.32
TSHR P16473 2/20 0.32
KDM4E B2RXH2 3/20 0.30
LMNA P02545 2/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30
ALDH1A1 P00352 3/20 0.30
HPGD P15428 1/20 0.30
POLB P06746 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17297444 0.96 MAPT (0.32) MAPTTSHRKDM4ELMNAMAPK1
SCHEMBL18688048 0.94 MAPT (0.32) MAPTTSHRKDM4ELMNAMAPK1
SCHEMBL19986002 0.94 MAPT (0.33) MAPTTSHRKDM4ELMNAMAPK1
SCHEMBL19986188 0.94 MAPT (0.34) MAPTTSHRKDM4ELMNAMAPK1
SCHEMBL17305775 0.92 MAPT (0.32) MAPTTSHRKDM4ELMNAMAPK1
SCHEMBL17305734 0.91 MAPT (0.32) MAPTTSHRKDM4ELMNAMAPK1
SCHEMBL17305659 0.91 MAPT (0.32) MAPTTSHRKDM4ELMNAMAPK1
SCHEMBL17297459 0.91 MAPT (0.33) MAPTTSHRKDM4ELMNAMAPK1
SCHEMBL17297535 0.91 MAPT (0.32) MAPTTSHRKDM4ELMNAMAPK1
SCHEMBL17297403 0.89 MAPT (0.34) MAPTTSHRKDM4ELMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed