Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 7/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934901 | 0.89 | FEN1 (0.38) | HTR2CHTR2BHTR2APTGDRPTGDR2 | |
| SCHEMBL19986348 | 0.88 | CYP3A4 (0.36) | CYP3A4CYP2C9APPFFAR4S1PR1 | |
| SCHEMBL19985414 | 0.88 | HTR2C (0.38) | HTR2CHTR2BFFAR4HTR2APDE4A | |
| SCHEMBL19985420 | 0.86 | HTR2C (0.38) | CYP3A4CYP2C9HTR2CHTR2BFFAR4 | |
| SCHEMBL19986430 | 0.85 | CYP3A4 (0.38) | CYP3A4CYP2C9APPFFAR4S1PR1 | |
| SCHEMBL15681366 | 0.84 | CYP3A4 (0.43) | CYP3A4CYP2C9APPFFAR4S1PR1 | |
| SCHEMBL19985425 | 0.84 | CYP2C9 (0.39) | CYP2C9HTR2CHTR2BHTR2APDE4A | |
| SCHEMBL8934201 | 0.84 | PTGDR2 (0.41) | HTR2CHTR2BFFAR4HTR2APTGDR | |
| SCHEMBL19986349 | 0.83 | CYP3A4 (0.39) | CYP3A4CYP2C9APPFFAR4S1PR1 | |
| SCHEMBL16769035 | 0.83 | CYP3A4 (0.41) | CYP3A4CYP2C9APPFFAR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079959-A1 | LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY | DIC CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |