Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19982648 | 0.78 | KMT2A (0.49) | KMT2ATDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL21332156 | 0.77 | MAOB (0.57) | KMT2ATDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL30722248 | 0.77 | MAOB (0.57) | KMT2ATDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL19970812 | 0.77 | KMT2A (0.48) | KMT2ATDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL22784072 | 0.75 | ABCB1 (0.60) | KMT2ATDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL30758793 | 0.75 | ABCB1 (0.60) | KMT2ATDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL433401 | 0.74 | CCNB2 (0.72) | KMT2ATDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL29537861 | 0.74 | CCNB2 (0.72) | KMT2ATDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL30804539 | 0.74 | MAOB (0.57) | KMT2ATDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL1163495 | 0.74 | MAOB (0.57) | KMT2ATDP1L3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296297-A1 | BENZIMIDAZOL DERIVATIVES FOR TREATING FILOVIRUS INFECTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-21 | — | — | EP | disclosed |