Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986932 | 0.90 | KDM4E (0.32) | LMNAKDM4EALDH1A1POLBHPGD | |
| SCHEMBL19986870 | 0.86 | KDM4E (0.34) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL29979932 | 0.86 | KDM4E (0.34) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL19974190 | 0.85 | SLC22A2 (0.35) | LMNAKDM4EALDH1A1POLBHPGD | |
| SCHEMBL19974021 | 0.84 | EPHA2 (0.34) | LMNACYP2C9KDM4EALDH1A1POLB | |
| SCHEMBL19986948 | 0.81 | KMT2A (0.35) | LMNACYP2C9KDM4EALDH1A1POLB | |
| SCHEMBL19987109 | 0.79 | POLB (0.33) | LMNACYP2C9KDM4EALDH1A1POLB | |
| SCHEMBL19987107 | 0.77 | PDE4A (0.33) | LMNAKDM4EALDH1A1POLBHPGD | |
| SCHEMBL28904868 | 0.77 | KDM4E (0.32) | LMNAKDM4EALDH1A1POLBHPGD | |
| SCHEMBL19986916 | 0.76 | KMT2A (0.35) | LMNACYP2C9KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512849-B1 | 7-SUBSTITUTED 1-ARYL-NAPHTHYRIDIN-3-CARBOXAMIDES AND THEIR USE | BAYER AG (DE) | 2021-06-23 | — | — | EP | disclosed |
| WO-2018050510-A1 | 7-SUBSTITUTED 1-ARYL-NAPHTHYRIDINE-3-CARBOXYLIC ACID AMIDES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-03-22 | — | — | WO | disclosed |