Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 18/20 | 0.73 |
| ▸ | FYN | P06241 | 2/20 | 0.61 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13234283 | 0.88 | PIM1 (0.79) | PIM1FYNPIM2KCNH2 | |
| SCHEMBL22421521 | 0.86 | PIM1 (0.78) | PIM1FYNPIM2KCNH2 | |
| SCHEMBL19987040 | 0.86 | PIM1 (0.75) | PIM1FYNPIM2KCNH2 | |
| SCHEMBL102173 | 0.85 | PIM1 (1.00) | PIM1FYNPIM2KCNH2 | |
| SCHEMBL14653588 | 0.84 | PIM1 (1.00) | PIM1FYNPIM2KCNH2 | |
| SCHEMBL16211091 | 0.84 | PIM1 (1.00) | PIM1FYNPIM2KCNH2 | |
| SCHEMBL14653589 | 0.84 | PIM1 (1.00) | PIM1FYNPIM2KCNH2 | |
| SCHEMBL20794285 | 0.84 | PIM1 (1.00) | PIM1FYNPIM2KCNH2 | |
| SCHEMBL16210293 | 0.84 | PIM1 (1.00) | PIM1FYNPIM2KCNH2 | |
| SCHEMBL19986921 | 0.84 | PIM1 (0.79) | PIM1FYNPIM2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2734205-B1 | HETEROCYCLIC PROTEIN KINASE INHIBITORS | TOLERO PHARMACEUTICALS INC (US) | 2018-03-21 | — | — | EP | disclosed |