⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25565384 | 0.80 | — | — | |
| SCHEMBL26585401 | 0.80 | — | — | |
| SCHEMBL19708653 | 0.77 | — | — | |
| SCHEMBL18509818 | 0.77 | — | — | |
| SCHEMBL21467397 | 0.77 | — | — | |
| SCHEMBL19169746 | 0.74 | — | — | |
| SCHEMBL23279900 | 0.73 | — | — | |
| SCHEMBL18427602 | 0.71 | — | — | |
| SCHEMBL20009385 | 0.70 | KDM4E (0.32) | — | |
| SCHEMBL26049160 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312550-A1 | N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)-QUINOLINE-4-CARBOXAMIDES | ASTRAZENECA AB (SE) | 2023-10-05 | — | — | US | disclosed |
| US-20230203019-A1 | Piperazine Cyclic Ureas | SIRONAX (BEIJING) CO., LTD. (CN) | 2023-06-29 | — | — | US | disclosed |
| US-20230140238-A1 | ANTI-VIRAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-05-04 | — | — | US | disclosed |
| EP-2493890-B1 | NITROGEN-CONTAINING AROMATIC COMPOUNDS AND METAL COMPLEXES | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |