Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 19/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | CD99 | P14209 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987346 | 0.90 | NT5E (0.40) | NT5ECD99 | |
| SCHEMBL19987203 | 0.89 | NT5E (0.44) | NT5EPDE2ACD99 | |
| SCHEMBL19987260 | 0.84 | P2RY12 (0.39) | NT5E | |
| SCHEMBL19987313 | 0.84 | NT5E (0.44) | NT5EPDE2ACD99 | |
| SCHEMBL19987157 | 0.84 | NT5E (0.44) | NT5EPDE2ACD99 | |
| SCHEMBL19987209 | 0.83 | NT5E (0.45) | NT5E | |
| SCHEMBL19987304 | 0.83 | CYP3A4 (0.36) | NT5E | |
| SCHEMBL21511172 | 0.82 | NT5E (0.48) | NT5E | |
| SCHEMBL19987322 | 0.82 | NT5E (0.36) | NT5E | |
| SCHEMBL19987169 | 0.82 | NT5E (0.42) | NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018049535-A1 | NUCLEOSIDE ANALOGUES AND METHODS OF USE THEREOF | LCB PHARMA INC. (CA) | 2018-03-22 | — | — | WO | disclosed |