Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 14/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17923542 | 1.00 | SLC22A2 (0.47) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL82201 | 1.00 | SLC22A2 (0.47) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL30232130 | 1.00 | SLC22A2 (0.47) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL81545 | 1.00 | SLC22A2 (0.47) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL29775433 | 1.00 | SLC22A2 (0.47) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL82290 | 0.98 | SLC22A2 (0.47) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL17748203 | 0.98 | SLC22A2 (0.47) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL29775463 | 0.98 | SLC22A2 (0.47) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL19307744 | 0.95 | SLC22A2 (0.47) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL82531 | 0.95 | SLC22A2 (0.47) | SLC22A2CYP3A4TMEM97ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3045206-B2 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY | VIIV HEALTHCARE CO (US) | 2023-02-15 | — | — | EP | disclosed |
| EP-3045206-B1 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY | VIIV HEALTHCARE CO (US) | 2018-03-28 | — | — | EP | disclosed |