Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 8/20 | 1.00 |
| ▸ | TET3 | O43151 | 2/20 | 1.00 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 1.00 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.56 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.56 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.56 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1993690 | 1.00 | TET2 (1.00) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL1993688 | 1.00 | TET2 (1.00) | TET2TET3TET1GRIK1GRIK2 | |
| Itaconate SCHEMBL11094945 | 0.80 | TET2 (0.65) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL14748207 | 0.78 | — | — | |
| SCHEMBL2158348 | 0.78 | — | — | |
| SCHEMBL19383760 | 0.78 | — | — | |
| SCHEMBL11037132 | 0.78 | TET2 (0.64) | TET2TET3TET1GRIK1GRIK2 | |
| Malic Acid SCHEMBL14740593 | 0.77 | TET2 (0.61) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL6038448 | 0.74 | — | — | |
| SCHEMBL9510592 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338892-A1 | Prostate specific membrane antigen inhibitors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-06-29 | — | — | EP | disclosed |