SCHEMBL19991990

SCHEMBL19991990

Cc1nc(C(F)(F)F)cn1C(CC1CCCC1)C(=O)Nc1ccc(C(=O)OCc2ccccc2)cn1

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCK P35557 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12094210 1.00 GCK (0.55) GCK
SCHEMBL16705594 1.00 GCK (0.55) GCK
SCHEMBL16841479 0.90 GCK (0.47) GCK
SCHEMBL13244697 0.89 GCK (0.58) GCK
SCHEMBL13244706 0.88 GCK (0.57) GCK
SCHEMBL1712332 0.87 GCK (0.71) GCK
SCHEMBL1711889 0.87 GCK (0.71) GCK
SCHEMBL13244573 0.87 GCK (0.56) GCK
SCHEMBL27823205 0.85 GCK (0.76) GCK
SCHEMBL27823204 0.85 GCK (0.76) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2871180-B1 2-AMINONICOTINIC ACID ESTER DERIVATIVE AND BACTERICIDE CONTAINING SAME AS ACTIVE INGREDIENT AGRO KANESHO CO LTD (JP) 2018-03-21 EP disclosed
CN-102216276-A substituted heteroaryl PFIZER 2011-10-12 CN disclosed