Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 16/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 6/20 | 0.41 |
| ▸ | MAOA | P21397 | 6/20 | 0.41 |
| ▸ | MAOB | P27338 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21169469 | 1.00 | MEN1 (0.43) | MEN1KMT2AP2RY12KDM1AMAOA | |
| SCHEMBL21169458 | 1.00 | MEN1 (0.43) | MEN1KMT2AP2RY12KDM1AMAOA | |
| SCHEMBL19979444 | 0.89 | P2RY12 (0.51) | MEN1KMT2AP2RY12KDM1AMAOA | |
| SCHEMBL19992122 | 0.89 | MEN1 (0.49) | MEN1KMT2AP2RY12KDM1AMAOA | |
| SCHEMBL21169531 | 0.89 | MEN1 (0.49) | MEN1KMT2AP2RY12KDM1AMAOA | |
| SCHEMBL19992121 | 0.89 | MEN1 (0.49) | MEN1KMT2AP2RY12KDM1AMAOA | |
| SCHEMBL21169624 | 0.88 | MEN1 (0.50) | MEN1KMT2AP2RY12KDM1AMAOA | |
| SCHEMBL21169534 | 0.88 | MEN1 (0.50) | MEN1KMT2AP2RY12KDM1AMAOA | |
| SCHEMBL21160534 | 0.87 | MEN1 (0.54) | MEN1KMT2AP2RY12KDM1AMAOA | |
| SCHEMBL19992246 | 0.85 | MEN1 (0.50) | MEN1KMT2AP2RY12KDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050684-A1 | FUSED BICYCLIC INHIBITORS OF MENIN-MLL INTERACTION | JANSSEN PHARMACEUTICA NV (BE) | 2018-03-22 | — | — | WO | disclosed |